Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2327827 | 0.98 | KMT2A (0.47) | KMT2AMEN1ADAMTS7ATMPPP1CA | |
| SCHEMBL29874448 | 0.84 | GABRA2 (0.50) | KMT2AMEN1ADAMTS7KDM4ENPC1 | |
| SCHEMBL23367502 | 0.83 | ADAMTS7 (0.44) | KMT2AMEN1ADAMTS7HDAC1HDAC3 | |
| SCHEMBL23367526 | 0.83 | ADAMTS7 (0.44) | KMT2AMEN1ADAMTS7HDAC1HDAC3 | |
| SCHEMBL23367219 | 0.83 | RPA1 (0.40) | ADAMTS7HDAC1NPC1RAB9AP2RX7 | |
| SCHEMBL1752087 | 0.82 | P2RX7 (0.53) | KMT2AMEN1ADAMTS7HDAC1KDM4E | |
| SCHEMBL28090831 | 0.81 | MAPK14 (0.52) | KMT2AMEN1ADAMTS7HDAC1KDM4E | |
| SCHEMBL23354766 | 0.81 | ALDH1A1 (0.46) | HDAC1KDM4ENPC1RAB9AP2RX7 | |
| SCHEMBL18910106 | 0.81 | HDAC1 (0.39) | KMT2AMEN1ADAMTS7HDAC1KDM4E | |
| SCHEMBL15577164 | 0.81 | RPA1 (0.49) | KMT2AMEN1ADAMTS7ATMPPP1CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102985439-B | IAP BIR domain binding compounds | 制药科学股份有限公司 | 2016-06-15 | — | — | CN | disclosed |