Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 10/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 10/20 | 0.33 |
| ▸ | AHCY | P23526 | 1/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28029278 | 0.83 | ADORA2A (0.46) | — | |
| SCHEMBL4621403 | 0.80 | XDH (0.50) | — | |
| SCHEMBL27983442 | 0.80 | CDK1 (0.59) | CDK1CCNB1CCNE1CDK2HSP90AA1 | |
| SCHEMBL6013684 | 0.77 | CDK1 (0.54) | CDK1CCNB1CCNE1CDK2HSP90AA1 | |
| SCHEMBL28998309 | 0.76 | YTHDC1 (0.46) | — | |
| SCHEMBL15789757 | 0.74 | CDK1 (0.50) | CDK1CCNB1CCNE1CDK2HSP90AA1 | |
| SCHEMBL1825531 | 0.71 | XDH (0.51) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL28788637 | 0.70 | CDK1 (0.43) | CDK1CCNB1CCNE1CDK2HSP90AA1 | |
| SCHEMBL7626823 | 0.70 | CDK1 (0.44) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL28480707 | 0.69 | CDK1 (0.47) | CDK1CCNB1CCNE1CDK2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658800-A | CNS delivery of MRNA and uses thereof | 夏尔人类遗传性治疗公司 | 2016-06-08 | — | — | CN | disclosed |