Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17584763 | 0.88 | MEN1 (0.59) | MEN1KMT2AXDHALDH1A1HPGD | |
| SCHEMBL17141308 | 0.79 | MEN1 (0.51) | MEN1KMT2AXDHALDH1A1KDM4E | |
| SCHEMBL10166458 | 0.75 | ALOX15 (0.70) | ALDH1A1HPGDPTGS2ATMKDM4E | |
| SCHEMBL10508211 | 0.75 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1HPGDPTGS2 | |
| SCHEMBL31438211 | 0.75 | ERBB2 (0.68) | MEN1KMT2AXDHALDH1A1HPGD | |
| SCHEMBL408607 | 0.74 | TGFBR1 (0.56) | MEN1KMT2AALDH1A1HPGDATM | |
| SCHEMBL17141287 | 0.74 | TUBB4A (0.57) | MEN1KMT2ALMNAMAPT | |
| SCHEMBL10814624 | 0.74 | MEN1 (0.77) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL28058395 | 0.74 | MAPK8 (0.49) | LMNATDP1MAPT | |
| SCHEMBL5223142 | 0.73 | MEN1 (0.53) | MEN1KMT2AXDHALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669569-B | A kind of synthetic method of the triazole compounds of NH 1,2,3 | 武汉工程大学 | 2017-12-12 | — | — | CN | disclosed |
| CN-105669569-A | Synthesis method of NH-1,2,3-triazole compound | 武汉工程大学 | 2016-06-15 | — | — | CN | disclosed |