Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 6/20 | 0.48 |
| ▸ | CNR1 | P21554 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2811635 | 0.83 | PTGER4 (0.45) | SMN1; SMN2ALDH1A1CNR2CNR1PTGER4 | |
| SCHEMBL13132252 | 0.83 | PTGER4 (0.45) | SMN1; SMN2ALDH1A1CNR2CNR1PTGER4 | |
| SCHEMBL2813588 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1KMT2ACNR2CNR1 | |
| SCHEMBL30564140 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1KMT2ACNR2CNR1 | |
| SCHEMBL13132278 | 0.75 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1KMT2ACNR2CNR1 | |
| SCHEMBL12526801 | 0.72 | PDE4A (0.47) | SMN1; SMN2ALDH1A1KMT2ACNR2CNR1 | |
| SCHEMBL12523932 | 0.71 | REN (0.47) | SMN1; SMN2ALDH1A1KMT2ACNR2CNR1 | |
| SCHEMBL3350382 | 0.70 | CNR1 (0.50) | SMN1; SMN2ALDH1A1KMT2ACNR2CNR1 | |
| SCHEMBL90348 | 0.69 | CNR2 (0.71) | SMN1; SMN2ALDH1A1KMT2ACNR2CNR1 | |
| SCHEMBL8247540 | 0.69 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1CNR2CNR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8975252-B2 | Morpholine derivative | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2015-03-10 | — | — | US | disclosed |
| US-20100240644-A1 | MORPHOLINE DERIVATIVE | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240644-A1 | MORPHOLINE DERIVATIVE | REN, AGTR1, AGTR2 | SMN1; SMN2 3903/4885ALDH1A1 2202/4885KMT2A 1278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.