Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.60 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3228582 | 0.83 | APP (0.82) | APPALDH1A1SMN1; SMN2MAOBMAOA | |
| SCHEMBL5390877 | 0.83 | MAPT (0.54) | ALDH1A1LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL28532263 | 0.83 | MAPT (0.61) | ALDH1A1LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL12952784 | 0.81 | MAPT (0.47) | ALDH1A1LMNAHTTNCOA1NCOA3 | |
| SCHEMBL31011691 | 0.81 | ALDH1A1 (0.51) | ALDH1A1LMNAHTTNCOA1NCOA3 | |
| SCHEMBL14880488 | 0.80 | KCNJ1 (0.63) | APPALDH1A1LMNAHTTNCOA1 | |
| SCHEMBL5791490 | 0.80 | MAPT (0.59) | APPALDH1A1LMNAHTTMAPT | |
| SCHEMBL20328414 | 0.80 | APP (0.70) | APPALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL20328415 | 0.80 | APP (0.70) | APPALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL492221 | 0.80 | APP (0.70) | APPALDH1A1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646396-B | A kind of synthetic method of benzothiazole derivant | 上海应用技术学院 | 2018-09-14 | — | — | CN | disclosed |
| CN-105646396-A | Method for synthesizing benzothiazole derivatives | 上海应用技术学院 | 2016-06-08 | — | — | CN | disclosed |