Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.70 |
| ▸ | MAOB | P27338 | 3/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3228582 | 0.91 | APP (0.82) | APPMAOBMAOAALDH1A1MEN1 | |
| SCHEMBL19059386 | 0.85 | APP (0.74) | APPMAOBMAOAALDH1A1NPC1 | |
| SCHEMBL11044221 | 0.85 | APP (0.74) | APPMAOBMAOAALDH1A1NPC1 | |
| SCHEMBL5122923 | 0.84 | ALDH1A1 (0.80) | APPMAOBMAOAALDH1A1MEN1 | |
| SCHEMBL28526426 | 0.84 | APP (0.72) | APPMAOBMAOAALDH1A1NPC1 | |
| SCHEMBL18475586 | 0.82 | APP (1.00) | APPMAOBMAOAALDH1A1NPC1 | |
| SCHEMBL12945246 | 0.82 | APP (0.70) | APPMAOBMAOAALDH1A1MEN1 | |
| SCHEMBL11044220 | 0.82 | APP (0.70) | APPMAOBMAOAALDH1A1MEN1 | |
| SCHEMBL9475495 | 0.82 | APP (0.70) | APPMAOBMAOANPC1RAB9A | |
| SCHEMBL2272164 | 0.81 | APP (0.69) | APPMAOBMAOAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646396-B | A kind of synthetic method of benzothiazole derivant | 上海应用技术学院 | 2018-09-14 | — | — | CN | disclosed |
| CN-105646396-A | Method for synthesizing benzothiazole derivatives | 上海应用技术学院 | 2016-06-08 | — | — | CN | disclosed |