Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 2/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26630176 | 0.78 | GSK3B (0.52) | ACVR1CHEK1AURKADAPK3JAK2 | |
| SCHEMBL8488571 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDLMNACYP1A2 | |
| SCHEMBL5506950 | 0.74 | CHEK1 (0.50) | ACVR1CHEK1AURKADAPK3JAK2 | |
| SCHEMBL3982954 | 0.70 | ALDH1A1 (0.37) | ACVR1CHEK1AURKADAPK3JAK2 | |
| Ammonia Solution, Strong SCHEMBL4541709 | 0.70 | ALDH1A1 (0.37) | ACVR1CHEK1AURKADAPK3JAK2 | |
| SCHEMBL22667212 | 0.69 | MEN1 (0.54) | ACVR1NQO2ALDH1A1KDM4EHPGD | |
| SCHEMBL12085466 | 0.69 | KDM4E (0.46) | ACVR1NQO2ALDH1A1KDM4EHPGD | |
| SCHEMBL5505355 | 0.69 | CYP19A1 (0.43) | ACVR1CHEK1AURKADAPK3JAK2 | |
| SCHEMBL20548712 | 0.68 | CYP19A1 (0.39) | ACVR1CHEK1AURKADAPK3JAK2 | |
| SCHEMBL8244853 | 0.68 | NQO2 (0.43) | ACVR1NQO2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105764341-A | Use of substituted dihydrooxindole sulfonamides or salts thereof for increasing stress tolerance in plants | 拜耳作物科学股份公司 | 2016-07-13 | — | — | CN | disclosed |