Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24664741 | 0.86 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDEGFRNPSR1 | |
| SCHEMBL16822181 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDEGFRNPSR1 | |
| Hydrochloric Acid SCHEMBL16822115 | 0.83 | MEN1 (0.47) | ALDH1A1KDM4EHPGDEGFRNPSR1 | |
| SCHEMBL8998975 | 0.81 | EGFR (0.72) | ALDH1A1KDM4EHPGDEGFRNPSR1 | |
| SCHEMBL8525601 | 0.79 | MEN1 (0.43) | ALDH1A1HPGDNPSR1CDC25AMEN1 | |
| SCHEMBL8998910 | 0.79 | EGFR (0.60) | ALDH1A1KDM4EHPGDEGFRNPSR1 | |
| SCHEMBL9818249 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDEGFRNPSR1 | |
| SCHEMBL27369982 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDEGFRNPSR1 | |
| SCHEMBL24665805 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDEGFRNPSR1 | |
| Hydrochloric Acid SCHEMBL27717556 | 0.78 | MEN1 (0.42) | ALDH1A1HPGDNPSR1CDC25AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022198196-A1 | INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2022-09-22 | — | — | WO | disclosed |
| CN-105764341-A | Use of substituted dihydrooxindole sulfonamides or salts thereof for increasing stress tolerance in plants | 拜耳作物科学股份公司 | 2016-07-13 | — | — | CN | disclosed |
| WO-1999062900-A1 | OXINDOLE DERIVATIVES USED AS NEUROKININ RECEPTOR ANTAGONISTS | SANOFI-SYNTHELABO (FR) | 1999-12-09 | — | — | WO | disclosed |