Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP12 | P39900 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28243455 | 0.93 | MMP2 (0.40) | MMP2MMP9MMP12KCNH2NPSR1 | |
| SCHEMBL28242604 | 0.89 | APP (0.44) | MMP2MMP9MMP12NPSR1APP | |
| SCHEMBL28242719 | 0.82 | APP (0.41) | MMP2MMP9MMP12NPSR1APP | |
| SCHEMBL30669395 | 0.81 | MMP2 (0.51) | MMP2MMP9MMP12KCNH2CSNK1E | |
| SCHEMBL9277673 | 0.81 | MMP2 (0.51) | MMP2MMP9MMP12KCNH2CSNK1E | |
| SCHEMBL6744835 | 0.79 | MMP2 (0.49) | MMP2MMP9MMP12KCNH2CSNK1E | |
| SCHEMBL30524148 | 0.77 | MMP2 (0.44) | MMP2MMP9MMP12KCNH2CSNK1E | |
| SCHEMBL614604 | 0.75 | KMT2A (0.42) | MMP2MMP9MMP12NPSR1KMT2A | |
| SCHEMBL15562662 | 0.75 | LTA4H (0.36) | MMP2MMP9MMP12CSNK1EMEN1 | |
| SCHEMBL5804621 | 0.75 | CSNK1E (0.48) | MMP2MMP9MMP12KCNH2CSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646528-A | Soluble bithiophene derivative and preparation and application thereof | 中国中化股份有限公司 | 2016-06-08 | — | — | CN | claimed |
| CN-105646528-B | A kind of solubility thiophthene derivative and its preparation and application | 中国中化股份有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-105646528-A | Soluble bithiophene derivative and preparation and application thereof | 中国中化股份有限公司 | 2016-06-08 | — | — | CN | disclosed |