Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP12 | P39900 | 2/20 | 0.49 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30669395 | 0.98 | MMP2 (0.51) | MMP2MMP9MMP12CSNK1EKMT2A | |
| SCHEMBL9277673 | 0.98 | MMP2 (0.51) | MMP2MMP9MMP12CSNK1EKMT2A | |
| SCHEMBL12003637 | 0.95 | MMP12 (0.43) | MMP2MMP9MMP12CSNK1EKMT2A | |
| SCHEMBL614604 | 0.89 | KMT2A (0.42) | MMP2MMP9MMP12KMT2ANPC1 | |
| Tetrabuthylammonium SCHEMBL29130286 | 0.85 | MMP2 (0.44) | MMP2MMP9MMP12CSNK1ECNR2 | |
| SCHEMBL29144869 | 0.84 | APP (0.37) | MMP2MMP9MMP12KMT2ALMNA | |
| Tetrabuthylammonium SCHEMBL29130287 | 0.84 | MMP2 (0.44) | MMP2MMP9MMP12CSNK1ECNR2 | |
| SCHEMBL5804621 | 0.81 | CSNK1E (0.48) | MMP2MMP9MMP12CSNK1EKMT2A | |
| SCHEMBL2569114 | 0.81 | LMNA (0.48) | MMP2MMP9MMP12KMT2ANPC1 | |
| SCHEMBL30524148 | 0.79 | MMP2 (0.44) | MMP2MMP9MMP12CSNK1EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11174275-B2 | Methods for the preparation of cyclopentaoxasilinones and cyclopentaoxaborininones and their use | DREXEL UNIVERSITY (US) | 2021-11-16 | — | — | US | disclosed |
| US-20210054003-A1 | Methods for the preparation of cyclopentaoxasilinones and cyclopentaoxaborininones and their use | DREXEL UNIVERSITY | 2021-02-25 | — | — | US | disclosed |
| US-6689905-B2 | REACTING 2,6-DIMETHYL-3-OXO-BICYCLO(2.2.1)HEPTANE-1-CARBOXYLIC ACID, SEPARATING THE DIASTEREOMERS USING REVERSED PHASE CHROMATOGRAPHY | WYETH | 2004-02-10 | — | — | US | disclosed |
| US-20030018211-A1 | Stereoisomers of 3-aminotricyclo[2.2.1.0(2.6)]heptane-1,3-dicarboxylic acid | WYETH | 2003-01-23 | — | — | US | disclosed |
| WO-2003002513-A1 | STEREOISOMERS OF 3-AMINOTRICYCLO[2.2.1.0(2,6)]HEPTANE-1,3-DICARBOXYLIC ACID | WYETH (US) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11174275-B2 | Methods for the preparation of cyclopentaoxasilinones and cyclopentaoxaborininones and their use | HSD17B7, CYP4A22, PPOX | MMP2 2914/4885MMP9 2637/4885MMP12 3192/4885 |
| US-20030018211-A1 | Stereoisomers of 3-aminotricyclo[2.2.1.0(2.6)]heptane-1,3-dicarboxylic acid | SLC10A1, PKD1, SLC10A2 | MMP2 3745/4885MMP9 3431/4885MMP12 4528/4885 |
| US-20210054003-A1 | Methods for the preparation of cyclopentaoxasilinones and cyclopentaoxaborininones and their use | HSD17B7, CYP4A22, PPOX | MMP2 2914/4885MMP9 2637/4885MMP12 3192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.