Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070914 | 0.93 | MMP2 (0.47) | MMP2MMP9MMP12APPHTR2A | |
| SCHEMBL28242604 | 0.93 | APP (0.44) | MMP2MMP9MMP12APPHTR2A | |
| SCHEMBL28242719 | 0.85 | APP (0.41) | MMP2MMP9MMP12APPHTR2A | |
| SCHEMBL15562662 | 0.81 | LTA4H (0.36) | MMP2MMP9MMP12LTA4HSMN1; SMN2 | |
| SCHEMBL12003637 | 0.80 | MMP12 (0.43) | MMP2MMP9MMP12APPHTR2A | |
| SCHEMBL20368207 | 0.80 | HTR2A (0.42) | MMP2MMP9MMP12APPHTR2A | |
| SCHEMBL5431806 | 0.79 | MMP12 (0.40) | MMP2MMP9MMP12APPHTR2A | |
| SCHEMBL29144873 | 0.79 | MMP2 (0.40) | MMP2MMP9MMP12APPHTR2A | |
| SCHEMBL614604 | 0.78 | KMT2A (0.42) | MMP2MMP9MMP12APPHTR2A | |
| SCHEMBL15562697 | 0.77 | LTA4H (0.38) | MMP2MMP9MMP12LTA4HSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646528-B | A kind of solubility thiophthene derivative and its preparation and application | 中国中化股份有限公司 | 2018-09-28 | — | — | CN | disclosed |