Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL28071030 | 0.81 | DRD3 (0.36) | KDM4EALDH1A1GAA | |
| Ethoxycarbonyl Group SCHEMBL28070920 | 0.77 | NLRP3 (0.37) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL28082108 | 0.73 | — | — | |
| SCHEMBL28070921 | 0.71 | FYN (0.37) | — | |
| Ethoxycarbonyl Group SCHEMBL27835612 | 0.70 | ADH1A (0.33) | — | |
| Cyclopentanol SCHEMBL27904360 | 0.69 | TSHR (0.43) | ALDH1A1 | |
| SCHEMBL17949696 | 0.68 | FYN (0.38) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL28808107 | 0.67 | — | — | |
| SCHEMBL16836044 | 0.67 | KDM4E (0.56) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL3225173 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814062-A | Spiro-oxazolones | 豪夫迈·罗氏有限公司 | 2016-07-27 | — | — | CN | disclosed |