Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727862 | 0.79 | KMT2A (0.42) | L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL21243279 | 0.79 | HTT (0.42) | L3MBTL1MMP8POLBHTTKMT2A | |
| SCHEMBL1521208 | 0.76 | MMP8 (0.45) | L3MBTL1MMP8POLBHTTKMT2A | |
| SCHEMBL9165581 | 0.72 | L3MBTL1 (0.43) | L3MBTL1MMP8POLBHTTKMT2A | |
| SCHEMBL5640387 | 0.72 | LMNA (0.46) | POLBKMT2ALMNAMEN1KDM4E | |
| SCHEMBL9165582 | 0.72 | L3MBTL1 (0.43) | L3MBTL1MMP8POLBHTTKMT2A | |
| SCHEMBL8536881 | 0.72 | L3MBTL1 (0.43) | L3MBTL1MMP8POLBHTTKMT2A | |
| SCHEMBL7292294 | 0.69 | L3MBTL1 (0.41) | L3MBTL1MMP8POLBHTTKMT2A | |
| SCHEMBL3368388 | 0.69 | AOC3 (0.42) | POLBHTTLMNASMN1; SMN2KDM4E | |
| SCHEMBL6972092 | 0.69 | L3MBTL1 (0.42) | L3MBTL1MMP8POLBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105813653-A | Methylene carbamate linkers for use with target-drug conjugates | 西雅图基因公司 | 2016-07-27 | — | — | CN | disclosed |