Acetic Acid Methyl Ester

Acetic Acid Methyl Ester

SCHEMBL28071128

COC(C)=O.Fc1cc(F)cc(F)c1

nearest known ligand 0.56

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
CES2 O00748 2/20 0.48
CES1 P23141 2/20 0.48
CYP4F2 P78329 1/20 0.44
CYP4A11 Q02928 1/20 0.44
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA9 Q16790 1/20 0.41
SLC6A3 Q01959 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
KDM4E B2RXH2 1/20 0.36
IDO1 P14902 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid Methyl Ester SCHEMBL27871275 0.82 ALDH1A1 (0.42) ALDH1A1CES2CES1CYP4F2CYP4A11
Acetic Acid SCHEMBL27478470 0.79 CES2 (0.55) ALDH1A1CES2CES1CYP4F2CYP4A11
SCHEMBL1995396 0.77 CYP4F2 (0.69) ALDH1A1CES2CES1CYP4F2CYP4A11
Fluorobenzene SCHEMBL28789208 0.77 TSHR (0.48) ALDH1A1SLC6A3SMN1; SMN2NPC1RAB9A
SCHEMBL521670 0.77 CA1 (0.58) ALDH1A1CES2CES1CA12CA1
Methoxymethane SCHEMBL27837378 0.75 CA12 (0.47) ALDH1A1CES2CES1CA12CA1
Acetic Acid Methyl Ester SCHEMBL8322448 0.74 ALDH1A1 (1.00) ALDH1A1CA1KDM4E
Acetic Acid Methyl Ester SCHEMBL3650 0.74
Acetic Acid Methyl Ester SCHEMBL3080739 0.74
Acetic Acid Methyl Ester SCHEMBL28296965 0.74 ALDH1A1 (1.00) ALDH1A1CA1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107011326-B Fungicidal pyrazoles compound FMC公司 2019-11-12 CN disclosed
CN-106008299-B It is used to prepare the intermediate of antifungal pyrazoles 杜邦公司 2018-05-11 CN disclosed
CN-106417305-A Fungicidal pyrazoles and their mixtures 杜邦公司 2017-02-22 CN disclosed
CN-106008299-A Intermediate for preparing fungicidal pyrazoles 杜邦公司 2016-10-12 CN disclosed
CN-103140136-B9 Fungicidal pyrazoles and mixtures thereof 杜邦公司 2016-06-29 CN disclosed
CN-103140136-B fungicidal pyrazoles and mixtures thereof DUPONT (US) 2016-05-11 CN disclosed
CN-103140136-A Fungicidal pyrazoles and mixtures thereof DU PONT 2013-06-05 CN disclosed