SCHEMBL2807116

SCHEMBL2807116

C=C(C)C(=O)OC(OC)[Si](OCC)(OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
THRB P10828 1/20 0.37
TSHR P16473 3/20 0.35
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1253678 0.79 TSHR (0.41) ALDH1A1THRBTSHR
SCHEMBL25276153 0.77 THRB (0.38) ALDH1A1THRBTSHR
SCHEMBL138292 0.77 THRB (0.38) ALDH1A1THRBTSHR
Methyl Alcohol SCHEMBL28830048 0.76 THRB (0.37) ALDH1A1THRBTSHR
SCHEMBL5082391 0.76 TSHR (0.39) ALDH1A1THRBTSHR
Hydrogen Sulfide SCHEMBL4951624 0.76 THRB (0.37) ALDH1A1THRBTSHR
SCHEMBL11464441 0.76 ALDH1A1 (0.34) ALDH1A1THRBTSHR
Alcohol SCHEMBL28598934 0.75 THRB (0.36) ALDH1A1THRBTSHR
SCHEMBL5711487 0.75 ALDH1A1 (0.36) ALDH1A1THRBTSHR
SCHEMBL16537247 0.72 TSHR (0.40) ALDH1A1THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9289359-B2 Self-adhesive multicomponent dental material IVOCLAR VIVADENT AG (LI) 2016-03-22 US disclosed
EP-2233123-A1 Self-adhesive multi-component dental material Ivoclar Vivadent AG (LI) 2010-09-29 EP disclosed
US-20100240795-A1 SELF-ADHESIVE MULTICOMPONENT DENTAL MATERIAL IVOCLAR VIVADENT AG (LI) 2010-09-23 US disclosed