Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1253678 | 0.82 | TSHR (0.41) | TSHRTHRBALDH1A1 | |
| SCHEMBL1720257 | 0.80 | ALDH1A1 (0.41) | TSHRALDH1A1 | |
| SCHEMBL25276153 | 0.77 | THRB (0.38) | TSHRTHRBALDH1A1 | |
| SCHEMBL138292 | 0.77 | THRB (0.38) | TSHRTHRBALDH1A1 | |
| Hydrogen Sulfide SCHEMBL4951624 | 0.76 | THRB (0.37) | TSHRTHRBALDH1A1 | |
| Methyl Alcohol SCHEMBL28830048 | 0.76 | THRB (0.37) | TSHRTHRBALDH1A1 | |
| SCHEMBL2807116 | 0.76 | ALDH1A1 (0.38) | TSHRTHRBALDH1A1 | |
| SCHEMBL5711487 | 0.75 | ALDH1A1 (0.36) | TSHRTHRBALDH1A1 | |
| Alcohol SCHEMBL28598934 | 0.75 | THRB (0.36) | TSHRTHRBALDH1A1 | |
| SCHEMBL1719297 | 0.74 | TSHR (0.39) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008128819-A1 | MIXTURE CONTAINING ORGANOSILICON COMPOUND AND USE THEREOF | EVONIK DEGUSSA GMBH (DE) | 2008-10-30 | — | — | WO | disclosed |