Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16667998 | 0.98 | PKM (0.38) | PKMMMP8CYP1A2KDM4ECYP4F2 | |
| SCHEMBL18430092 | 0.79 | PKM (0.43) | PKMMMP8CYP1A2KDM4ECYP4F2 | |
| SCHEMBL26095606 | 0.78 | DGAT1 (0.42) | GAAMEN1KMT2A | |
| SCHEMBL3700953 | 0.78 | CYP4F2 (0.42) | PKMMMP8KDM4ECYP4F2CYP4A11 | |
| SCHEMBL8397654 | 0.78 | SMN1; SMN2 (0.40) | PKMMMP8CYP1A2KDM4ECYP4F2 | |
| SCHEMBL28010269 | 0.77 | MMP8 (0.39) | PKMMMP8CYP1A2KDM4ECYP4F2 | |
| SCHEMBL28606353 | 0.76 | PKM (0.43) | PKMMMP8CYP1A2KDM4ECYP4F2 | |
| SCHEMBL31251984 | 0.75 | PKM (0.43) | PKMMMP8CYP1A2KDM4ECYP4F2 | |
| SCHEMBL16668362 | 0.75 | TDP1 (0.47) | PKMCYP1A2KDM4ETHRBGAA | |
| SCHEMBL26452808 | 0.74 | PAOX (0.37) | KDM4EGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105683188-A | Ring-fused bicyclic pyridyl derivatives as FGFR4 inhibitors | 诺华股份有限公司 | 2016-06-15 | — | — | CN | disclosed |