SCHEMBL28010269

SCHEMBL28010269

CCOC(=O)C(NCCN)(C(C)C)C(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.39
CYP1A2 P05177 1/20 0.35
PKM P14618 3/20 0.35
KDM4E B2RXH2 1/20 0.35
THRB P10828 1/20 0.34
ALOX15 P16050 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
HTT P42858 1/20 0.33
CPB2 Q96IY4 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CYP4F2 P78329 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28071202 0.77 PKM (0.39) MMP8CYP1A2PKMKDM4ETHRB
Hydrochloric Acid SCHEMBL16667998 0.75 PKM (0.38) MMP8CYP1A2PKMKDM4ETHRB
SCHEMBL11379622 0.67 METAP2 (0.40) CYP1A2ALOX15MGAMGAASI
SCHEMBL27884262 0.67 MMP8 (0.43) MMP8CYP1A2PKMKDM4ETHRB
SCHEMBL235893 0.66 MMP8 (0.46) MMP8CYP1A2PKMKDM4ETHRB
SCHEMBL13662690 0.66 MMP8 (0.50) MMP8CYP1A2PKMKDM4ETHRB
SCHEMBL6589761 0.66 MMP8 (0.46) MMP8CYP1A2PKMKDM4ETHRB
SCHEMBL22519700 0.66 CYP4F2 (0.58) MMP8CYP1A2PKMKDM4ETHRB
SCHEMBL27443603 0.66 CYP1A2 (0.42) CYP1A2ALOX15MGAMGAASI
SCHEMBL15474405 0.66 MMP8 (0.46) MMP8CYP1A2PKMKDM4ETHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104557561-A Method for preparing N1,N1-diisoprylamino ethylamine or salts of N1,N1-diisoprylamino ethylamine BEIJING YUEKANGKECHUANG MEDICAL TECHNOLOGY CO LTD 2015-04-29 CN claimed