Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734535 | 0.72 | EPHX1 (0.35) | HSD17B10ALDH1A1EPHX2HSD11B1 | |
| SCHEMBL6742682 | 0.70 | THRB (0.36) | ALDH1A1TSHREPHX2HSD11B1L3MBTL1 | |
| SCHEMBL9260496 | 0.69 | KDM4E (0.56) | ALDH1A1KMT2AMEN1HSD11B1 | |
| SCHEMBL3929216 | 0.69 | ALDH1A1 (0.38) | ALDH1A1TSHREPHX2SMN1; SMN2 | |
| SCHEMBL161518 | 0.67 | THRB (0.38) | ALDH1A1TSHREPHX2HSD11B1SMN1; SMN2 | |
| SCHEMBL27976720 | 0.66 | MAPK1 (0.42) | EPHX2KMT2AMEN1HSD11B1 | |
| SCHEMBL2019240 | 0.65 | THRB (0.32) | EPHX2HSD11B1 | |
| SCHEMBL28396623 | 0.65 | THRB (0.32) | EPHX2HSD11B1 | |
| SCHEMBL7747476 | 0.65 | DPP4 (0.47) | ALDH1A1EPHX2 | |
| SCHEMBL7750318 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102453001-B | Thiomorpholine compounds and its production and use | INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2016-06-01 | — | — | CN | disclosed |