Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6742682 | 0.81 | THRB (0.36) | EPHX1EPHX2ALDH1A1HSD11B1HTT | |
| SCHEMBL3929216 | 0.79 | ALDH1A1 (0.38) | EPHX1EPHX2ALDH1A1NPC1LMNA | |
| SCHEMBL28087061 | 0.78 | THRB (0.38) | EPHX1EPHX2ALDH1A1HSD11B1NPC1 | |
| SCHEMBL161518 | 0.78 | THRB (0.38) | EPHX1EPHX2ALDH1A1HSD11B1LMNA | |
| SCHEMBL27976720 | 0.76 | MAPK1 (0.42) | EPHX2HSD11B1CYP2C9 | |
| SCHEMBL28396623 | 0.75 | THRB (0.32) | EPHX1EPHX2HSD11B1THRBCYP2C9 | |
| SCHEMBL2019240 | 0.75 | THRB (0.32) | EPHX1EPHX2HSD11B1THRBCYP2C9 | |
| SCHEMBL31160481 | 0.75 | KMT2A (0.35) | EPHX1EPHX2ALDH1A1HSD11B1LMNA | |
| SCHEMBL28071496 | 0.72 | HSD17B10 (0.35) | EPHX2ALDH1A1HSD11B1HSD17B10 | |
| SCHEMBL678264 | 0.69 | GRIN2D (0.33) | EPHX1EPHX2LMNATHRBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990634-B1 | ACYLATING AGENTS, ACYLATION METHOD WITH THE USE OF THE SAME AND ADAMANTANE DERIVATIVES | DAICEL CHEM (JP) | 2013-04-10 | — | — | EP | disclosed |
| US-6429314-B1 | USING 1,2-DICARBONYL DERIVATIVE OR ITS HYDROXY REDUCTIVE, OXYGEN, COBALT ACETATE METAL COMPOUND, AND N-HYDROXYPHTHALIMIDE OR OTHER IMIDE DERIVATIVE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-08-06 | — | — | US | disclosed |
| EP-0990634-A1 | ACYLATING AGENTS, ACYLATION METHOD WITH THE USE OF THE SAME AND ADAMANTANE DERIVATIVES | Daicel Chemical Industries, Ltd. (JP) | 2000-04-05 | — | — | EP | disclosed |