SCHEMBL28072057

SCHEMBL28072057

CCC(c1ccccc1)C(CC)(c1ccccc1)C(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
ESR1 P03372 1/20 0.33
KCNN4 O15554 1/20 0.33
MEN1 O00255 5/20 0.33
KMT2A Q03164 5/20 0.33
NPC1 O15118 1/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 2/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
MIF P14174 1/20 0.33
POLB P06746 2/20 0.32
HKDC1 Q2TB90 1/20 0.32
TRPA1 O75762 1/20 0.32
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GRIN1 Q05586 4/20 0.31
GRIN2A Q12879 4/20 0.31
GRIN2D O15399 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9631838 0.76 AOC3 (0.39) LMNAKCNN4MEN1KMT2ANPC1
SCHEMBL756001 0.76 LMNA (0.42) LMNAKCNN4MEN1KMT2ANPC1
SCHEMBL28248384 0.75 LMNA (0.45) LMNAKCNN4MEN1KMT2ANPC1
SCHEMBL756292 0.75 LMNA (0.45) LMNAKCNN4MEN1KMT2ANPC1
SCHEMBL10325656 0.74 LMNA (0.41) LMNAESR1KCNN4MEN1KMT2A
SCHEMBL1176305 0.73 LMNA (0.43) LMNAKCNN4MEN1KMT2ANPC1
Phosphine SCHEMBL10951511 0.73 LMNA (0.43) LMNAKCNN4MEN1KMT2ANPC1
SCHEMBL11590303 0.73 LMNA (0.43) LMNAKCNN4MEN1KMT2ANPC1
SCHEMBL11588095 0.73 LMNA (0.43) LMNAKCNN4MEN1KMT2ANPC1
SCHEMBL9077582 0.73 LMNA (0.43) LMNAKCNN4MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108431061-B Process for producing functionalized ethylene-based polymers with low gel content 陶氏环球技术有限责任公司 2021-11-02 CN claimed
CN-107001737-B Process for preparing modified ethylene polymers using hydrocarbon initiators 陶氏环球技术有限责任公司 2020-12-01 CN claimed
CN-108431061-A Method for producing functional ethylene's based polyalcohol with low-gel content 陶氏环球技术有限责任公司 2018-08-21 CN claimed
CN-107001737-A The method that modified ethylenic polymer is prepared using hydrocarbon initiator 陶氏环球技术有限责任公司 2017-08-01 CN claimed
CN-108431061-B Process for producing functionalized ethylene-based polymers with low gel content 陶氏环球技术有限责任公司 2021-11-02 CN disclosed
CN-107001737-B Process for preparing modified ethylene polymers using hydrocarbon initiators 陶氏环球技术有限责任公司 2020-12-01 CN disclosed
CN-108431061-A Method for producing functional ethylene's based polyalcohol with low-gel content 陶氏环球技术有限责任公司 2018-08-21 CN disclosed
CN-107001737-A The method that modified ethylenic polymer is prepared using hydrocarbon initiator 陶氏环球技术有限责任公司 2017-08-01 CN disclosed
CN-105793296-A Process for visbreaking propylene-based polymers with C-C initiators 陶氏环球技术有限责任公司 2016-07-20 CN disclosed