Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27872672 | 0.98 | CHRM2 (0.30) | ALOX15 | |
| SCHEMBL27855978 | 0.94 | ALOX15 (0.32) | ALOX15 | |
| SCHEMBL28258733 | 0.83 | — | — | |
| SCHEMBL28078720 | 0.82 | KEAP1 (0.31) | — | |
| SCHEMBL28118656 | 0.80 | — | — | |
| SCHEMBL1299354 | 0.80 | KCNK3 (0.39) | — | |
| SCHEMBL2560949 | 0.80 | HTT (0.34) | — | |
| SCHEMBL7297647 | 0.80 | — | — | |
| SCHEMBL2557029 | 0.78 | L3MBTL1 (0.47) | — | |
| SCHEMBL2552232 | 0.77 | OPRD1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103339141-B | C-28 amines of C-3 modified betulinic acid derivatives as HIV maturation inhibitors | 百时美施贵宝公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-102307872-B | BCL-2-selectively apoptosis-inducing agents for the treatment of cancer and immune diseases | ABBVIE 公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-103429607-B | There is the triterpenoid that C-17 and C-3 of HIV maturation inhibit activities is modified | BRISTOL-MYERS SQUIBB CO. (US) | 2016-02-17 | — | — | CN | disclosed |
| CN-102485721-B | 2，3-benzodiazine ketone compound replaced and uses thereof | CAO YA (CN) | 2015-12-09 | — | — | CN | disclosed |
| CN-102947285-B | Sulfonamide derivatives as BCL-2-selective apoptosis inducers for the treatment of cancer and immune diseases | ABBVIE (US) | 2015-08-26 | — | — | CN | disclosed |
| CN-103429607-A | C-17 and C-3 modified triterpenoids with HIV maturation inhibitory activity | BRISTOL MYERS SQUIBB CO | 2013-12-04 | — | — | CN | disclosed |
| CN-103339141-A | C-28 amines of c-3 modified betulinic acid derivatives as hiv maturation inhibitors | BRISTOL MYERS SQUIBB CO | 2013-10-02 | — | — | CN | disclosed |
| CN-102947285-A | Sulfonamide derivatives as BCL-2-selective apoptosis inducers for the treatment of cancer and immune diseases | ABBOTT LAB | 2013-02-27 | — | — | CN | disclosed |
| CN-102307872-A | BCL-2-selectively apoptosis-inducing agents for the treatment of cancer and immune diseases | ABBOTT LAB | 2012-01-04 | — | — | CN | disclosed |