Isopropylbenzene

Isopropylbenzene

SCHEMBL28072202

CC(C)c1ccccc1.CCCCCc1ccccc1.CCc1ccccc1CC.c1ccccc1

nearest known ligand 0.53

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.53
KCNH2 Q12809 2/20 0.51
RAB9A P51151 2/20 0.47
NPC1 O15118 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
SIGMAR1 Q99720 1/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
CYP2D6 P10635 1/20 0.43
KMT2A Q03164 1/20 0.43
EP300 Q09472 1/20 0.43
KAT5 Q92993 1/20 0.43
KAT8 Q9H7Z6 1/20 0.43
S1PR2 O95136 1/20 0.42
S1PR1 P21453 1/20 0.42
CHRM2 P08172 1/20 0.42
HTR1A P08908 1/20 0.42
ADRA2A P08913 1/20 0.42
CHRM1 P11229 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butylbenzyl SCHEMBL8519397 0.86 HTR2A (0.53) HTR2AKCNH2RAB9ANPC1SMN1; SMN2
SCHEMBL27670849 0.83 KCNH2 (0.57) HTR2AKCNH2SIGMAR1EP300KAT5
Butylbenzyl SCHEMBL27330531 0.82 ALDH1A1 (0.52) KCNH2SMN1; SMN2SIGMAR1ALDH1A1CHRM2
Isopropylbenzene SCHEMBL1451620 0.82 CRHBP (0.46) SMN1; SMN2KMT2ASLC6A2SLC6A4LMNA
Isopropylbenzene SCHEMBL27747785 0.82 CRHBP (0.46) SMN1; SMN2KMT2ASLC6A2SLC6A4LMNA
Isobutane SCHEMBL28163284 0.80 KCNH2 (0.61) HTR2AKCNH2SIGMAR1ALDH1A1CHRM2
Isopropylbenzene SCHEMBL8837125 0.80 HTR2A (0.47) HTR2AKCNH2ALDH1A1LMNA
SCHEMBL6548131 0.79 L3MBTL1 (0.50) KCNH2SIGMAR1KMT2ACHRM2HTR1A
SCHEMBL8091009 0.79 HTR2A (0.56) HTR2AKCNH2ALDH1A1CHRM2ADRA2A
Isopropylbenzene SCHEMBL10951391 0.79 SIGMAR1 (0.49) HTR2AKCNH2RAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105793447-A Scandium separation method 学校法人关西大学 2016-07-20 CN disclosed