SCHEMBL28072265

SCHEMBL28072265

Brc1nccnc1C1CNCCO1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.42
DRD3 P35462 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11142301 0.80
SCHEMBL5347558 0.76 DRD2 (0.46) DRD2DRD3
SCHEMBL23501813 0.75 SLC6A3 (0.40)
SCHEMBL28860435 0.75 DRD2 (0.41) DRD2DRD3
SCHEMBL28666083 0.74 DRD2 (0.50) DRD2DRD3
SCHEMBL28835937 0.74 MAPKAPK2 (0.38) DRD2DRD3
SCHEMBL5346309 0.74 SLC6A3 (0.46)
SCHEMBL28574471 0.73 DRD2 (0.39) DRD2DRD3
SCHEMBL28105993 0.73 DRD2 (0.42) DRD2DRD3
SCHEMBL27816652 0.73 DRD2 (0.42) DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105622526-A Preparation method of 2-aminopyrazine derivatives UNIV HUBEI TECHNOLOGY 2016-06-01 CN disclosed