SCHEMBL28835937

SCHEMBL28835937

c1cn2ccnc2c(C2CNCCO2)n1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPKAPK2 P49137 2/20 0.38
DRD2 P14416 1/20 0.37
DRD3 P35462 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11142301 0.74
SCHEMBL28072265 0.74 DRD2 (0.42) DRD2DRD3
Hydrochloric Acid SCHEMBL34474047 0.73 DRD2 (0.48) MAPKAPK2DRD2DRD3
SCHEMBL28666083 0.72 DRD2 (0.50) DRD2DRD3
SCHEMBL15552570 0.72 HTR2C (0.39)
SCHEMBL27816652 0.71 DRD2 (0.42) DRD2DRD3
SCHEMBL28105993 0.71 DRD2 (0.42) DRD2DRD3
SCHEMBL23501813 0.70 SLC6A3 (0.40)
SCHEMBL28860435 0.70 DRD2 (0.41) DRD2DRD3
SCHEMBL913262 0.69 DRD2 (0.46) DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114989177-B Preparation process of imidazopyrazine compound 江西瑞威尔生物科技有限公司 2023-01-24 CN disclosed
CN-114989177-A Preparation process of imidazopyrazine compound 江西瑞威尔生物科技有限公司 2022-09-02 CN disclosed