Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RUVBL1 | Q9Y265 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MPO | P05164 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | AKT1 | P31749 | 2/20 | 0.56 |
| ▸ | CDC7 | O00311 | 1/20 | 0.56 |
| ▸ | CHUK | O15111 | 1/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.56 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.56 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.56 |
| ▸ | PRKCG | P05129 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11860142 | 1.00 | RUVBL1 (0.65) | RUVBL1KDM4EMEN1LMNAMPO | |
| SCHEMBL9609465 | 0.92 | MEN1 (0.71) | RUVBL1KDM4EMEN1LMNAMPO | |
| SCHEMBL30767397 | 0.92 | MEN1 (0.71) | RUVBL1KDM4EMEN1LMNAMPO | |
| Hydrochloric Acid SCHEMBL19748758 | 0.92 | RUVBL1 (0.73) | RUVBL1KDM4EMEN1LMNAMPO | |
| SCHEMBL9610738 | 0.92 | MEN1 (0.71) | RUVBL1KDM4EMEN1LMNAMPO | |
| Hydrochloric Acid SCHEMBL21082966 | 0.90 | MEN1 (0.69) | RUVBL1KDM4EMEN1LMNAMPO | |
| Hydrochloric Acid SCHEMBL19747056 | 0.90 | MEN1 (0.69) | RUVBL1KDM4EMEN1LMNAMPO | |
| SCHEMBL8252240 | 0.88 | RUVBL1 (0.70) | RUVBL1KDM4EMEN1LMNAMPO | |
| SCHEMBL7035663 | 0.87 | RUVBL1 (0.66) | RUVBL1KDM4EMEN1LMNAMPO | |
| SCHEMBL6287113 | 0.87 | RUVBL1 (0.66) | RUVBL1KDM4EMEN1LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669520-A | Tryptophan basic skeleton-containing o-phenylenediamine selective histone deacetylase inhibitor and its preparation method and use | 山东大学 | 2016-06-15 | — | — | CN | disclosed |