Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | SGK1 | O00141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28072320 | 0.86 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10MAPTTAAR1 | |
| SCHEMBL11352247 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10MAPTEPAS1 | |
| SCHEMBL6964514 | 0.80 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10MAPTEPAS1 | |
| SCHEMBL28072438 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10MAPTEPAS1 | |
| SCHEMBL11359600 | 0.77 | ALDH1A1 (0.46) | KDM4EALDH1A1HSD17B10MAPTEPAS1 | |
| SCHEMBL29940995 | 0.77 | EPAS1 (0.54) | KDM4EALDH1A1HSD17B10MAPTEPAS1 | |
| SCHEMBL30987223 | 0.75 | MAPT (0.60) | KDM4EALDH1A1HSD17B10MAPTEPAS1 | |
| SCHEMBL28563540 | 0.75 | MAPT (0.60) | KDM4EALDH1A1HSD17B10MAPTEPAS1 | |
| SCHEMBL24566449 | 0.75 | MAPT (0.47) | KDM4EALDH1A1HSD17B10MAPTEPAS1 | |
| SCHEMBL28072318 | 0.75 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10MAPTLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669588-B | The preparation method of benzisothiazole analog derivative | 天津大学 | 2017-11-07 | — | — | CN | disclosed |
| CN-105669588-A | Preparation method of benzisothiazole derivative | 天津大学 | 2016-06-15 | — | — | CN | disclosed |