SCHEMBL2807287

SCHEMBL2807287

C#Cc1cc(C)c(O)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
ALDH1A1 P00352 2/20 0.38
TTR P02766 4/20 0.37
GAA P10253 2/20 0.36
KDM4E B2RXH2 2/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
PTGS1 P23219 4/20 0.35
PTGS2 P35354 4/20 0.35
ALOX5 P09917 4/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2C9 P11712 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
ACHE P22303 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9349821 0.80 HMGB1 (0.53) ALDH1A1GAAKDM4EMAPTCYP2C9
SCHEMBL12620797 0.78 CA1 (0.55) CA1CA2ESR1ESR2ALDH1A1
SCHEMBL2814698 0.74 CYP1A1 (0.33) CYP1A1CYP1B1
SCHEMBL6282292 0.74 CA1 (0.50) CA1CA2ESR1ESR2ALDH1A1
SCHEMBL2807671 0.74 ALDH1A1 (0.50) ALDH1A1GAAKDM4ELMNACYP3A4
SCHEMBL197918 0.74 TTR (0.58) CA1CA2ESR1ESR2ALDH1A1
SCHEMBL24132674 0.73 PGK1 (0.33) CYP1A1CYP1B1
SCHEMBL172851 0.73 TP53 (0.50) ESR1ESR2ALDH1A1KDM4EMAPT
SCHEMBL27211531 0.72 MEN1 (0.40) MEN1KMT2ACYP1A1CYP1B1
SCHEMBL27211532 0.72 MEN1 (0.40) MEN1KMT2ACYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286353-A1 ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF FUJIFILM CORPORATION (JP) 2010-11-11 US disclosed
US-20100240908-A1 ACETYLENE COMPOUND FUJIFILM CORPORATION (JP) 2010-09-23 US disclosed
EP-2202220-A1 ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF Fujifilm Corporation (JP) 2010-06-30 EP disclosed
EP-2202221-A1 ACETYLENE COMPOUND Fujifilm Corporation (JP) 2010-06-30 EP disclosed
EP-0420699-B1 Ferromagnetic member consiting of organic material CANON KK (JP) 1995-11-22 EP disclosed
US-5461132-A Organic magnetic member, organic ferromagnetic member, and process for producing the same, and time-responsible organic ferromagnetic member and process for controlling development of ferromagnetism CANON KABUSHIKI KAISHA (JP) 1995-10-24 US disclosed
EP-0420699-A2 Ferromagnetic member consiting of organic material CANON KABUSHIKI KAISHA (JP) 1991-04-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240908-A1 ACETYLENE COMPOUND NAT1, KATNA1, KAT2B CA1 1402/4885CA2 1282/4885ESR1 2920/4885
US-20100286353-A1 ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF KAT8, HDAC10, SSRP1 CA1 172/4885CA2 831/4885ESR1 3209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.