Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16676458 | 0.84 | MAPT (0.36) | DDR1MAPTSMN1; SMN2CCR2ADRA2A | |
| SCHEMBL27999924 | 0.79 | CCR2 (0.47) | DDR1SMN1; SMN2CCR2ADRA2AADRA2B | |
| SCHEMBL25456570 | 0.79 | CCR2 (0.43) | HDAC6MAPTSMN1; SMN2CCR2 | |
| Hydrochloric Acid SCHEMBL28000103 | 0.78 | CCR2 (0.46) | DDR1SMN1; SMN2CCR2ADRA2AADRA2B | |
| SCHEMBL25872926 | 0.78 | DDR1 (0.46) | HDAC6DDR1MAPTSMN1; SMN2CCR2 | |
| SCHEMBL28072988 | 0.75 | CYP1A2 (0.41) | MAPTSMN1; SMN2ADRA2AADRA2CADRA1D | |
| SCHEMBL28000085 | 0.75 | AOC3 (0.36) | HDAC6CCR2 | |
| SCHEMBL25302556 | 0.75 | PKM (0.43) | DDR1MAPTSMN1; SMN2 | |
| SCHEMBL25924438 | 0.74 | CHRNB2 (0.30) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL2416681 | 0.73 | TSHR (0.36) | DDR1MAPTSMN1; SMN2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105829285-A | Quinazolinone and isoquinolinone derivatives | 中外制药株式会社 | 2016-08-03 | — | — | CN | disclosed |