Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28073015 | 0.74 | HDAC6 (0.36) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL25456570 | 0.71 | CCR2 (0.43) | — | |
| SCHEMBL24289562 | 0.66 | STAT3 (0.41) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL24290481 | 0.66 | STAT3 (0.41) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL24576336 | 0.64 | GABRA1 (0.37) | — | |
| SCHEMBL12190764 | 0.64 | APP (0.37) | — | |
| SCHEMBL28705758 | 0.64 | MAPT (0.38) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19735030 | 0.62 | ALDH1A1 (0.41) | — | |
| SCHEMBL29661763 | 0.62 | ALDH1A1 (0.41) | — | |
| SCHEMBL20615440 | 0.61 | CHRNB2 (0.41) | CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |