SCHEMBL28073055

SCHEMBL28073055

Cc1ccc(-n2cncc2C=O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.42
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40
ALDH1A1 P00352 3/20 0.40
HCAR1 Q9BXC0 1/20 0.37
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
F2 P00734 1/20 0.35
ELANE P08246 1/20 0.35
CTSG P08311 1/20 0.35
CMA1 P23946 1/20 0.35
CTRC Q99895 1/20 0.35
PTK2 Q05397 1/20 0.35
CYP11B2 P19099 2/20 0.35
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17940683 0.84 HCAR1 (0.37) CYP2A6HSP90AA1ALDH1A1HCAR1CYP11B2
SCHEMBL4003442 0.82 ALDH1A1 (0.39) ALDH1A1CYP3A4CYP2D6CYP2C9CYP11B2
SCHEMBL27981339 0.82 HSD17B10 (0.42) HSP90AA1HSP90AB1ALDH1A1F2CYP11B2
SCHEMBL4836447 0.82 ALDH1A1 (0.41) HSP90AA1HSP90AB1ALDH1A1HCAR1CYP11B2
SCHEMBL7563960 0.81 ATM (0.53) CYP2A6HSP90AA1HSP90AB1ALDH1A1CYP3A4
SCHEMBL14167337 0.81 CYP11B1 (0.41) ALDH1A1CYP3A4CYP2D6CYP2C9CYP11B2
SCHEMBL17940712 0.80 MAPK14 (0.49) HSP90AA1ALDH1A1NPC1RAB9AXDH
SCHEMBL16099492 0.78 CYP11B2 (0.58) CYP11B2CYP11B1
SCHEMBL10589324 0.77 ALDH1A1 (0.46) ALDH1A1MEN1NPC1RAB9AKMT2A
SCHEMBL28073056 0.72 HSP90AA1 (0.43) HSP90AA1HSP90AB1ALDH1A1HCAR1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105820122-A Organic electroluminescent material and device 环球展览公司 2016-08-03 CN disclosed