SCHEMBL28073056

SCHEMBL28073056

Cc1ccccc1-n1cncc1C=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.43
HSP90AB1 P08238 1/20 0.43
HCAR1 Q9BXC0 1/20 0.40
ALDH1A1 P00352 4/20 0.37
TSHR P16473 1/20 0.37
PI4KA P42356 1/20 0.37
PI4K2B Q8TCG2 1/20 0.37
PI4K2A Q9BTU6 1/20 0.37
PI4KB Q9UBF8 1/20 0.37
MGLL Q99685 1/20 0.37
GAA P10253 1/20 0.36
GABRA5 P31644 3/20 0.35
FLT3 P36888 1/20 0.35
GSK3B P49841 1/20 0.35
GABRG2 P18507 2/20 0.35
GABRB3 P28472 2/20 0.35
GRM1 Q13255 1/20 0.35
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13180099 0.77 HSP90AA1 (0.48) HSP90AA1HSP90AB1HCAR1ALDH1A1TSHR
SCHEMBL15006750 0.76 POLB (0.46) HCAR1ALDH1A1KMT2AMEN1MAPT
SCHEMBL7563960 0.75 ATM (0.53) HSP90AA1HSP90AB1ALDH1A1GAAGABRA5
SCHEMBL28073055 0.72 CYP2A6 (0.42) HSP90AA1HSP90AB1HCAR1ALDH1A1MGLL
SCHEMBL17893848 0.72 ALDH1A1 (0.48) HSP90AA1HSP90AB1HCAR1ALDH1A1GRM1
SCHEMBL13145112 0.71 HSP90AA1 (0.53) HSP90AA1HSP90AB1HCAR1ALDH1A1TSHR
SCHEMBL4800521 0.71 HSP90AA1 (0.44) HSP90AA1HSP90AB1HCAR1ALDH1A1PI4KA
SCHEMBL22732231 0.71 HSP90AA1 (0.44) HSP90AA1HSP90AB1HCAR1ALDH1A1PI4KA
SCHEMBL17940712 0.71 MAPK14 (0.49) HSP90AA1ALDH1A1TSHRMGLLGRM1
SCHEMBL17940683 0.70 HCAR1 (0.37) HSP90AA1HCAR1ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105820122-A Organic electroluminescent material and device 环球展览公司 2016-08-03 CN disclosed