Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP12 | P39900 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | CPA1 | P15085 | 3/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | CPA3 | P15088 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1861755 | 0.82 | TRPA1 (0.65) | MMP2MMP9MMP12CPA1TRPA1 | |
| SCHEMBL6138407 | 0.82 | TRPA1 (0.65) | MMP2MMP9MMP12CPA1TRPA1 | |
| SCHEMBL10535065 | 0.82 | TRPA1 (0.65) | MMP2MMP9MMP12CPA1TRPA1 | |
| SCHEMBL4258389 | 0.81 | MMP12 (0.68) | MMP2MMP9MMP12FFAR1MMP13 | |
| SCHEMBL1139516 | 0.81 | MMP12 (0.68) | MMP2MMP9MMP12FFAR1MMP13 | |
| SCHEMBL6463393 | 0.81 | KMT2A (0.49) | MMP2MMP9MMP12PPARGPPARA | |
| SCHEMBL28823710 | 0.81 | MME (0.49) | MMEMMP2MMP9MMP12PPARG | |
| SCHEMBL6464257 | 0.81 | PPARG (0.53) | MMEPPARGPPARATRPA1 | |
| SCHEMBL6803856 | 0.81 | KMT2A (0.49) | MMP2MMP9MMP12PPARGPPARA | |
| SCHEMBL379630 | 0.79 | MMP12 (0.70) | MMP2MMP9MMP12PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029672-B | serine/threonine kinase inhibitors | 基因泰克公司 | 2019-03-29 | — | — | CN | disclosed |
| CN-106029672-A | Serine/threonine kinase inhibitors | 基因泰克公司 | 2016-10-12 | — | — | CN | disclosed |