SCHEMBL6463393

SCHEMBL6463393

Cc1ccc(CC(O)CC(=O)O)cc1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
PPARG P37231 2/20 0.46
PPARA Q07869 2/20 0.46
FFAR1 O14842 2/20 0.46
TRPA1 O75762 1/20 0.46
MMP12 P39900 3/20 0.45
MMP13 P45452 3/20 0.45
MMP2 P08253 1/20 0.45
MMP9 P14780 1/20 0.45
MMP14 P50281 1/20 0.45
SLC22A6 Q4U2R8 1/20 0.44
TRPV1 Q8NER1 1/20 0.44
CPA1 P15085 2/20 0.43
CPB1 P15086 1/20 0.43
CPA3 P15088 1/20 0.43
CPB2 Q96IY4 1/20 0.43
PSMB5 P28074 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6803856 1.00 KMT2A (0.49) KMT2AMEN1PPARGPPARAFFAR1
SCHEMBL11826750 0.95 MMP12 (0.53) KMT2AMEN1PPARGPPARAFFAR1
SCHEMBL18031709 0.85 ACACB (0.44) KMT2AMEN1PPARGPPARAFFAR1
SCHEMBL6807540 0.83 EPHX1 (0.43) KMT2AMEN1PPARGPPARATRPA1
SCHEMBL6138407 0.82 TRPA1 (0.65) TRPA1MMP12MMP13MMP2MMP9
SCHEMBL10535065 0.82 TRPA1 (0.65) TRPA1MMP12MMP13MMP2MMP9
SCHEMBL1861755 0.82 TRPA1 (0.65) TRPA1MMP12MMP13MMP2MMP9
SCHEMBL16452830 0.81 FFAR1 (0.51) KMT2APPARGPPARAFFAR1CPA3
SCHEMBL1139059 0.81 MMP12 (0.68) FFAR1MMP12MMP13MMP2MMP9
SCHEMBL11829029 0.81 PTGS1 (0.47) KMT2AMEN1FFAR1TRPA1MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10894121-B2 Small molecule dye for molecular imaging and photothermal therapy THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2021-01-19 US disclosed
US-20190192761-A1 SMALL MOLECULE DYE FOR MOLECULAR IMAGING AND PHOTOTHERMAL THERAPY UNITED STATES DEPARTMENT OF ENERGY 2019-06-27 US disclosed
US-20160244614-A1 SMALL MOLECULE DYE FOR MOLECULAR IMAGING AND PHOTOTHERMAL THERAPY UNITED STATES DEPARTMENT OF ENERGY 2016-08-25 US disclosed
US-20160244614-A1 SMALL MOLECULE DYE FOR MOLECULAR IMAGING AND PHOTOTHERMAL THERAPY UNITED STATES DEPARTMENT OF ENERGY 2016-08-25 US disclosed
US-6903233-B2 Process for producing optically active 3-halogenocarboxylic acid ester and 3-azidocarboxylic acid ester TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-06-07 US disclosed
US-20030225301-A1 Process for producing optically active 3-halogenocarboxylic acid ester and 3-azidocarboxylic acid ester TAKASAGO INTERNATIONAL CORPORATION (JP) 2003-12-04 US disclosed
EP-1344763-A1 Process for producing optically active 3-halogenocarboxylic acid esters and 3-azide-carboxylic acid esters Takasago International Corporation (JP) 2003-09-17 EP disclosed
US-3966801-A ANTIINFLAMMATORY AGENTS WILLIAM H. RORER, INC. (US) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030225301-A1 Process for producing optically active 3-halogenocarboxylic acid ester and 3-azidocarboxylic acid ester HDHD5, APEH, AOC3 KMT2A 2065/4885MEN1 2962/4885PPARG 2174/4885
US-10894121-B2 Small molecule dye for molecular imaging and photothermal therapy SLC7A5, SLC43A1, HCCS KMT2A 3629/4885MEN1 3446/4885PPARG 2447/4885
US-20190192761-A1 SMALL MOLECULE DYE FOR MOLECULAR IMAGING AND PHOTOTHERMAL THERAPY SLC7A5, SLC43A1, HCCS KMT2A 3629/4885MEN1 3446/4885PPARG 2447/4885
US-20160244614-A1 SMALL MOLECULE DYE FOR MOLECULAR IMAGING AND PHOTOTHERMAL THERAPY SLC7A5, SLC43A1, HCCS KMT2A 3629/4885MEN1 3446/4885PPARG 2447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.