Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | PTEN | P60484 | 1/20 | 0.39 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16798316 | 0.81 | NQO2 (0.50) | IDO1SIGMAR1CTSKNQO2CA1 | |
| SCHEMBL5729298 | 0.81 | GLS (0.54) | ACEFFAR1KEAP1CA12CA1 | |
| SCHEMBL7453149 | 0.80 | NFKB1 (0.46) | IDO1CTSSCTSKCTSLCTSB | |
| SCHEMBL698405 | 0.78 | NQO2 (0.49) | IDO1SIGMAR1CTSKNQO2CA1 | |
| SCHEMBL306849 | 0.76 | ITGB3 (0.52) | FFAR1 | |
| SCHEMBL209838 | 0.75 | GLS (0.52) | IDO1CA12CA1CA7CA14 | |
| SCHEMBL29952891 | 0.75 | GLS (0.52) | IDO1CA12CA1CA7CA14 | |
| SCHEMBL30684558 | 0.74 | PPARG (0.51) | SIGMAR1 | |
| SCHEMBL31235394 | 0.74 | NQO2 (0.48) | IDO1SIGMAR1CTSKNQO2CA1 | |
| SCHEMBL9525580 | 0.74 | KDM4A (0.48) | CTSSCTSKCTSBNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029672-A | Serine/threonine kinase inhibitors | 基因泰克公司 | 2016-10-12 | — | — | CN | disclosed |