Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FGR | P09769 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756746 | 0.82 | TTR (0.52) | TTRCES1DPP4KMT2AMEN1 | |
| SCHEMBL21848273 | 0.77 | TTR (0.50) | TTRCES1KMT2AMEN1CASP3 | |
| SCHEMBL1137933 | 0.77 | TTR (0.55) | TTRCES1DPP4KMT2AMEN1 | |
| SCHEMBL15206754 | 0.77 | TTR (0.50) | TTRCES1KMT2AMEN1CASP3 | |
| SCHEMBL754994 | 0.77 | CES1 (0.50) | TTRCES1KMT2AMEN1CASP3 | |
| SCHEMBL2290914 | 0.77 | TTR (0.50) | TTRCES1KMT2AMEN1CASP3 | |
| SCHEMBL14880102 | 0.77 | MEN1 (0.46) | TTRCES1DPP4KMT2AMEN1 | |
| SCHEMBL9728201 | 0.77 | ALDH1A1 (0.48) | CES1ADORA2APTPRCDPP4PABPC1 | |
| SCHEMBL28074698 | 0.76 | TTR (0.48) | TTRCES1DPP4KMT2AMEN1 | |
| SCHEMBL30067921 | 0.74 | TTR (0.47) | TTRCES1KMT2AMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105732476-B | A kind of carbazole isatin type compound and its preparation method and purposes | 吉首大学 | 2017-12-01 | — | — | CN | disclosed |
| CN-105732476-A | Carbazole-isatin type compound and preparation method and application thereof | 吉首大学 | 2016-07-06 | — | — | CN | disclosed |