Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10045010 | 0.95 | TTR (0.47) | TTRCES1MGLLTP53LMNA | |
| SCHEMBL14901093 | 0.84 | TP53 (0.38) | TTRCES1MGLLTP53LMNA | |
| SCHEMBL28490612 | 0.82 | NR1H2 (0.54) | TTRCES1ALDH1A1 | |
| SCHEMBL9728198 | 0.80 | MGLL (0.42) | MGLLTP53LMNAMEN1KMT2A | |
| SCHEMBL13607734 | 0.79 | PARP1 (0.40) | TTRCES1LMNAMEN1KMT2A | |
| SCHEMBL7756746 | 0.77 | TTR (0.52) | TTRCES1MGLLLMNAMEN1 | |
| SCHEMBL15206754 | 0.76 | TTR (0.50) | TTRCES1MGLLLMNAMEN1 | |
| SCHEMBL21848273 | 0.76 | TTR (0.50) | TTRCES1MGLLMEN1KMT2A | |
| SCHEMBL2290914 | 0.76 | TTR (0.50) | TTRCES1MGLLMEN1KMT2A | |
| SCHEMBL28074688 | 0.76 | TTR (0.50) | TTRCES1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105732476-B | A kind of carbazole isatin type compound and its preparation method and purposes | 吉首大学 | 2017-12-01 | — | — | CN | disclosed |
| CN-105732476-A | Carbazole-isatin type compound and preparation method and application thereof | 吉首大学 | 2016-07-06 | — | — | CN | disclosed |