Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28074698 | 0.80 | TTR (0.48) | MGLLLMNAMAPTTP53GABRA1 | |
| SCHEMBL10045010 | 0.75 | TTR (0.47) | MGLLLMNAMAPTTP53GABRA1 | |
| SCHEMBL28551734 | 0.71 | MGLL (0.36) | MGLLLMNAMAPTTP53GABRA1 | |
| SCHEMBL14901093 | 0.69 | TP53 (0.38) | MGLLLMNAMAPTTP53GABRA1 | |
| SCHEMBL29717667 | 0.67 | ALDH1A1 (0.44) | MGLLMAPTTP53MEN1KMT2A | |
| SCHEMBL18900024 | 0.67 | LMNA (0.44) | MGLLLMNAMAPTGABRA1GABRB2 | |
| SCHEMBL29711265 | 0.66 | CES1 (0.59) | ALDH1A1 | |
| SCHEMBL10883505 | 0.66 | MAOA (0.48) | LMNAMAPTGABRA1GABRB2ANPEP | |
| SCHEMBL2259762 | 0.66 | CES1 (0.59) | ALDH1A1 | |
| SCHEMBL18983060 | 0.66 | MAPT (0.46) | LMNAMAPTGABRA1GABRB2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151518-A | N-arylation of isatins | ABBOTT LABORATORIES (US) | 1992-09-29 | — | — | US | disclosed |