Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.67 |
| ▸ | CA1 | P00915 | 2/20 | 0.67 |
| ▸ | CA2 | P00918 | 2/20 | 0.67 |
| ▸ | CA9 | Q16790 | 2/20 | 0.67 |
| ▸ | ACHE | P22303 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5659376 | 0.86 | ACHE (0.69) | ACHEMAPTTP53HSP90AA1CHRM5 | |
| SCHEMBL9096325 | 0.85 | ALDH1A1 (0.60) | CA12CA1CA2CA9ACHE | |
| SCHEMBL28070700 | 0.84 | ACHE (0.66) | CA12CA1CA2CA9ACHE | |
| SCHEMBL5659656 | 0.84 | ACHE (0.66) | CA12CA1CA2CA9ACHE | |
| SCHEMBL13627924 | 0.84 | CA12 (0.49) | CA12CA1CA2CA9ACHE | |
| SCHEMBL18954909 | 0.83 | ALDH1A1 (0.71) | CA12CA1CA2CA9ACHE | |
| SCHEMBL18954858 | 0.82 | ACHE (0.63) | ACHEMAPTTP53HSP90AA1CHRM5 | |
| SCHEMBL5658723 | 0.81 | ACHE (0.62) | CA12CA1CA2CA9ACHE | |
| SCHEMBL18954575 | 0.81 | CA1 (0.78) | CA12CA1CA2CA9ACHE | |
| SCHEMBL578250 | 0.80 | ACHE (0.74) | CA12CA1CA2CA9ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105732476-A | Carbazole-isatin type compound and preparation method and application thereof | 吉首大学 | 2016-07-06 | — | — | CN | disclosed |