Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28075277 | 0.85 | CA12 (0.67) | ALDH1A1ALDH3A1CA12CA1CA2 | |
| SCHEMBL9096191 | 0.84 | DRD2 (0.62) | ALDH1A1ALDH3A1MAPTACHELMNA | |
| Hydrochloric Acid SCHEMBL9096767 | 0.83 | DRD2 (0.61) | ALDH1A1ALDH3A1MAPTACHELMNA | |
| SCHEMBL9098897 | 0.82 | ALDH3A1 (0.57) | ALDH1A1ALDH3A1CA12CA1CA2 | |
| SCHEMBL9094274 | 0.82 | ALDH1A1 (0.62) | ALDH1A1ALDH3A1CA1CA2CA9 | |
| SCHEMBL9382409 | 0.80 | DRD2 (0.49) | ALDH1A1ALDH3A1KMT2ADRD2DRD4 | |
| SCHEMBL9094820 | 0.78 | ALDH1A1 (0.60) | ALDH1A1ALDH3A1MAPTACHELMNA | |
| SCHEMBL9095464 | 0.78 | ALDH1A1 (0.60) | ALDH1A1ALDH3A1MAPTACHELMNA | |
| Hydrochloric Acid SCHEMBL9096336 | 0.77 | ALDH1A1 (0.58) | ALDH1A1ALDH3A1MAPTACHELMNA | |
| SCHEMBL16798708 | 0.76 | ALDH3A1 (1.00) | ALDH1A1ALDH3A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585378-A | Composition containing an oxoindole compound | AKTIEBOLAGET ASTRA (SE) | 1996-12-17 | — | — | US | disclosed |
| EP-0624156-A1 | ISATIN DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Astra Aktiebolag (SE) | 1994-11-17 | — | — | EP | disclosed |
| WO-1993012085-A1 | ISATIN DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | AKTIEBOLAGET ASTRA (SE) | 1993-06-24 | — | — | WO | disclosed |