Phosphoric Acid

Phosphoric Acid

SCHEMBL28075580

Nc1cccc(N)c1.O=P(O)(O)O

nearest known ligand 0.67

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.67
CASP1 P29466 1/20 0.67
RECQL P46063 1/20 0.67
ALDH1A1 P00352 6/20 0.52
TDP1 Q9NUW8 3/20 0.52
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
CA7 P43166 1/20 0.52
PBRM1 Q86U86 1/20 0.52
HSD17B10 Q99714 2/20 0.48
TSHR P16473 1/20 0.48
F2 P00734 1/20 0.48
PLG P00747 1/20 0.48
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48
DDX3X O00571 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL28307474 0.84 CYP3A4 (0.46) CYP3A4CASP1RECQLALDH1A1TDP1
Phosphoric Acid SCHEMBL28306326 0.84 CYP3A4 (0.46) CYP3A4CASP1RECQLALDH1A1TDP1
Phosphoric Acid SCHEMBL28306329 0.84 CYP3A4 (0.46) CYP3A4CASP1RECQLALDH1A1TDP1
Phosphoric Acid SCHEMBL28412292 0.84 CYP3A4 (0.46) CYP3A4CASP1RECQLALDH1A1TDP1
SCHEMBL16054 0.82
SCHEMBL1934399 0.82 CYP3A4 (1.00) CYP3A4CASP1RECQLALDH1A1TDP1
SCHEMBL11661863 0.82 CYP3A4 (1.00) CYP3A4CASP1RECQLALDH1A1TDP1
SCHEMBL15158299 0.80 CYP3A4 (0.48) CYP3A4CASP1RECQLALDH1A1TDP1
SCHEMBL176968 0.80 CA2 (0.52) CYP3A4CASP1RECQLALDH1A1TDP1
Phosphoric Acid SCHEMBL10628319 0.80 ENPP2 (0.50) CYP3A4CASP1RECQLPBRM1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114591457-A Method for preparing two-dimensional polymer based on hydrogen bond effect 安徽大学 2022-06-07 CN claimed
CN-119775823-A Long-afterglow anti-counterfeiting ink composition and preparation method thereof 华侨大学 2025-04-08 CN disclosed
CN-116239116-A Method for preparing heteroatom doped porous carbon material with high specific surface area by ion activation method and application thereof 厦门稀土材料研究所 2023-06-09 CN disclosed
CN-106008962-A High-molecular-weight water-soluble aramid fibers and application thereof 中国乐凯集团有限公司 2016-10-12 CN disclosed