Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28075580 | 0.84 | CYP3A4 (0.67) | CYP3A4CASP1RECQLPBRM1ALDH1A1 | |
| Phosphoric Acid SCHEMBL28412292 | 0.74 | CYP3A4 (0.46) | CYP3A4CASP1RECQLPBRM1ALDH1A1 | |
| Phosphoric Acid SCHEMBL28306329 | 0.74 | CYP3A4 (0.46) | CYP3A4CASP1RECQLPBRM1ALDH1A1 | |
| Phosphoric Acid SCHEMBL28306326 | 0.74 | CYP3A4 (0.46) | CYP3A4CASP1RECQLPBRM1ALDH1A1 | |
| SCHEMBL15158299 | 0.71 | CYP3A4 (0.48) | CYP3A4CASP1RECQLPBRM1ALDH1A1 | |
| SCHEMBL176968 | 0.71 | CA2 (0.52) | CYP3A4CASP1RECQLPBRM1ALDH1A1 | |
| SCHEMBL29410980 | 0.71 | CYP3A4 (0.48) | CYP3A4CASP1RECQLPBRM1ALDH1A1 | |
| Phosphoric Acid SCHEMBL10628319 | 0.71 | ENPP2 (0.50) | CYP3A4CASP1RECQLPBRM1TSHR | |
| Aniline SCHEMBL5334646 | 0.71 | TSHR (0.65) | CYP3A4PBRM1TDP1CA2HSD17B10 | |
| Phosphoric Acid SCHEMBL29043954 | 0.71 | CA2 (0.50) | ALDH1A1CA12CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041739-A | A kind of efficient corrosion resisting oversize graphene aqueous slurry and preparation method thereof | 砥创(苏州)新材料科技有限公司 | 2019-07-23 | — | — | CN | claimed |
| CN-110041739-A | A kind of efficient corrosion resisting oversize graphene aqueous slurry and preparation method thereof | 砥创(苏州)新材料科技有限公司 | 2019-07-23 | — | — | CN | disclosed |