Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PER2 | O15055 | 2/20 | 0.34 |
| ▸ | CRY1 | Q16526 | 2/20 | 0.34 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2810321 | 0.85 | MAPK8 (0.42) | KDM4EALDH1A1KDM4CHSD17B10PTGER4 | |
| SCHEMBL27774890 | 0.83 | AR (0.43) | KDM4EALDH1A1ARKDM4CHSD17B10 | |
| SCHEMBL19597374 | 0.82 | ADORA2A (0.42) | KDM4EALDH1A1ARKDM4CHSD17B10 | |
| SCHEMBL2809192 | 0.82 | ALDH1A1 (0.46) | KDM4EALDH1A1KDM4CHSD17B10PTGER4 | |
| SCHEMBL15791921 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1ARKDM4CHSD17B10 | |
| SCHEMBL13131355 | 0.80 | KDM4C (0.38) | KDM4EALDH1A1KDM4CHSD17B10PER2 | |
| SCHEMBL2807452 | 0.80 | KDM4C (0.38) | KDM4EALDH1A1KDM4CHSD17B10PER2 | |
| SCHEMBL2806451 | 0.76 | ELANE (0.45) | KDM4EKDM4CHSD17B10TP53L3MBTL1 | |
| SCHEMBL15902179 | 0.75 | ALDH1A1 (0.51) | KDM4EALDH1A1ARKDM4CHSD17B10 | |
| SCHEMBL8241203 | 0.73 | ALDH1A1 (0.58) | KDM4EALDH1A1ACHEL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8975252-B2 | Morpholine derivative | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2015-03-10 | — | — | US | disclosed |
| US-20100240644-A1 | MORPHOLINE DERIVATIVE | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240644-A1 | MORPHOLINE DERIVATIVE | REN, AGTR1, AGTR2 | KDM4E 689/4885ALDH1A1 2202/4885AR 500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.