SCHEMBL1054548

SCHEMBL1054548

c1ccc2c(c1)-c1cccc3ccnc-2c13

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.73
ALDH1A1 P00352 5/20 0.56
MAPK1 P28482 4/20 0.56
TSHR P16473 3/20 0.56
HSD17B10 Q99714 3/20 0.56
ATM Q13315 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
CASP1 P29466 3/20 0.45
CASP7 P55210 2/20 0.45
CYP3A4 P08684 1/20 0.45
PABPC1 P11940 1/20 0.45
DNMT1 P26358 1/20 0.45
HPGD P15428 2/20 0.45
HIF1A Q16665 2/20 0.45
TP53 P04637 1/20 0.45
BCHE P06276 1/20 0.42
KDM4E B2RXH2 2/20 0.40
GAA P10253 1/20 0.40
CTSL P07711 1/20 0.39
PTPRC P08575 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29644349 1.00 MAOA (0.73) MAOAALDH1A1MAPK1TSHRHSD17B10
SCHEMBL23972209 1.00 MAOA (0.73) MAOAALDH1A1MAPK1TSHRHSD17B10
Fluoranthene SCHEMBL11227281 0.98 MAOA (0.71) MAOAALDH1A1MAPK1TSHRHSD17B10
Eupolauridine SCHEMBL3125284 0.87 MAOA (0.66) MAOAALDH1A1MAPK1TSHRHSD17B10
SCHEMBL21734529 0.85 MAOA (0.56) MAOAALDH1A1MAPK1TSHRHSD17B10
SCHEMBL1969983 0.85 MAOA (1.00) MAOAALDH1A1CASP1CASP7CYP3A4
SCHEMBL29869412 0.85 MAOA (0.75) MAOAALDH1A1MAPK1TSHRHSD17B10
SCHEMBL25380689 0.85 MAOA (0.75) MAOAALDH1A1MAPK1TSHRHSD17B10
SCHEMBL30416588 0.83 MAOA (0.97) MAOAALDH1A1CASP1CASP7CYP3A4
SCHEMBL28075835 0.83 MAOA (0.97) MAOAALDH1A1CASP1CASP7CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119588950-A Preparation method of metal organic coordination polymer mediated silver nanowire 深圳市源利电子新材料有限公司 2025-03-11 CN claimed
CN-114456167-A Azafluoranthene derivative and application thereof 上海八亿时空先进材料有限公司 2022-05-10 CN claimed
US-10833281-B2 Organic electroluminescence composition, material for organic electroluminescence element, solution of material for organic electroluminescence element, and organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2020-11-10 US claimed
US-20160329505-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, INK COMPOSITION, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-11-10 US claimed
US-8652656-B2 Triphenylene silane hosts UNIVERSAL DISPLAY CORPORATION (US) 2014-02-18 US claimed
US-20130119353-A1 TRIPHENYLENE SILANE HOSTS UNIVERSAL DISPLAY CORPORATION (US) 2013-05-16 US claimed
US-7662487-B2 Azaaromatic compounds having azafluoranthene skeletons and organic electroluminescent devices made by using the same IDEMITSU KOSAN CO., LTD. (JP) 2010-02-16 US claimed
US-20080206597-A1 AZAAROMATIC COMPOUNDS HAVING AZAFLUORANTHENE SKELETONS AND ORGANIC ELECTROLUMINESCENT DEVICES MADE BY USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-08-28 US claimed
EP-0409003-B1 Derivatives of compounds containing a carbonyl group conjugated to an aromatic moiety and electrophilic methods of fabrication thereof IBM (US) 1996-02-07 EP claimed
US-5462628-A Conditioning surface of polymeric material by reducing, bring two surfaces together to form interphase, reoxidizing INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1995-10-31 US claimed
US-5443865-A Method for conditioning a substrate for subsequent electroless metal deposition INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1995-08-22 US claimed
EP-0374487-B1 Method for conditioning an organic polymeric material IBM (US) 1994-06-29 EP claimed
US-5242713-A Metallizing polyimide film INTERNATIONAL BUSINESS MACHINES CORPORATION 1993-09-07 US claimed
US-5203955-A Supplying electrons to redox sites of a polymer and then dissolving the polymer in an aprotic solvent INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1993-04-20 US claimed
US-5045159-A Derivatives of compounds containing a carbonyl group conjugated to an aromatic moiety and electrophilic methods of fabrication thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1991-09-03 US claimed
US-5021129-A Multilayer structures of different electroactive materials and methods of fabrication thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1991-06-04 US claimed
EP-0409003-A2 Derivatives of compounds containing a carbonyl group conjugated to an aromatic moiety and electrophilic methods of fabrication thereof International Business Machines Corporation (US) 1991-01-23 EP claimed
US-12577455-B2 Photochromic compound, photochromic composition, photochromic article and spectacles HOYA LENS THAILAND LTD. (TH) 2026-03-17 US disclosed
US-4171443-A 10B-Azafluoranthene derivatives and precursors thereof AYERST, MCKENNA & HARRISON LIMITED (CA) 1979-10-16 US disclosed
US-4171443-A 10B-Azafluoranthene derivatives and precursors thereof AYERST, MCKENNA & HARRISON LIMITED (CA) 1979-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10833281-B2 Organic electroluminescence composition, material for organic electroluminescence element, solution of material for organic electroluminescence element, and organic electroluminescence element SLCO4C1, SLCO2A1, SLCO1A2 MAOA 1200/4885ALDH1A1 2178/4885MAPK1 1896/4885
US-20130119353-A1 TRIPHENYLENE SILANE HOSTS OCIAD2, OCIAD1, YAP1 MAOA 2515/4885ALDH1A1 3482/4885MAPK1 3737/4885
US-20080206597-A1 AZAAROMATIC COMPOUNDS HAVING AZAFLUORANTHENE SKELETONS AND ORGANIC ELECTROLUMINESCENT DEVICES MADE BY USING THE SAME DERL1, CTCF, ERAL1 MAOA 1747/4885ALDH1A1 456/4885MAPK1 1881/4885
US-20160329505-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, INK COMPOSITION, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE LEF1, BMI1, L1CAM MAOA 649/4885ALDH1A1 398/4885MAPK1 148/4885
US-12577455-B2 Photochromic compound, photochromic composition, photochromic article and spectacles CRY1, HBG1, ALDH1A2 MAOA 1437/4885ALDH1A1 126/4885MAPK1 1864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.