SCHEMBL28076068

SCHEMBL28076068

Brc1cc(Br)cc(-c2ccc3[nH]cnc3c2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
QPCT Q16769 5/20 0.41
QPCTL Q9NXS2 4/20 0.41
MAPT P10636 3/20 0.40
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 1/20 0.40
APEX1 P27695 1/20 0.40
RECQL P46063 1/20 0.40
BLM P54132 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
PRKCI P41743 1/20 0.38
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
RAB9A P51151 1/20 0.38
CHEK1 O14757 1/20 0.38
PIM1 P11309 1/20 0.38
AKT1 P31749 1/20 0.38
FLT3 P36888 1/20 0.38
PIM3 Q86V86 1/20 0.38
RAD52 P43351 1/20 0.37
PSMD11 O00231 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31143361 0.87 MAPT (0.50) QPCTQPCTLMAPTKDM4EALDH1A1
SCHEMBL6008269 0.87 MAPT (0.50) QPCTQPCTLMAPTKDM4EALDH1A1
SCHEMBL28178103 0.86 IDO1 (0.50) QPCTQPCTLMAPTKDM4EALDH1A1
SCHEMBL28076069 0.86 QPCT (0.55) QPCTQPCTLMAPTKDM4EALDH1A1
SCHEMBL2474515 0.79 QPCT (0.60) QPCTQPCTLMAPTKDM4EALDH1A1
SCHEMBL10757 0.79 CHEK1 (0.52) QPCTMAPTKDM4EALDH1A1APEX1
SCHEMBL29908911 0.79 CHEK1 (0.52) QPCTMAPTKDM4EALDH1A1APEX1
SCHEMBL28190280 0.79 QPCT (0.47) QPCTQPCTLMAPTKDM4EALDH1A1
SCHEMBL2457365 0.78 QPCT (0.50) QPCTQPCTLMAPTKDM4EALDH1A1
SCHEMBL11224144 0.77 BRD4 (0.40) QPCTQPCTLMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114315840-A 4H-imidazo [1,2-a ] imidazoles for electronic applications UDC 爱尔兰有限责任公司 2022-04-12 CN disclosed
CN-106188065-B 4H-imidazo [1,2-a ] imidazoles for electronic applications UDC 爱尔兰有限责任公司 2021-12-28 CN disclosed
CN-108440531-A 4H- imidazos [1,2-a] imidazoles for electronic application UDC 爱尔兰有限责任公司 2018-08-24 CN disclosed
CN-108299439-A 4H- imidazos [1,2-a] imidazoles for electronic application UDC 爱尔兰有限责任公司 2018-07-20 CN disclosed
CN-103917542-B 4H-imidazo [1,2-a ] imidazoles for electronic applications UDC 爱尔兰有限责任公司 2018-03-27 CN disclosed
CN-106188065-A 4H imidazo [1,2 a] imidazoles for electronic application 巴斯夫欧洲公司 2016-12-07 CN disclosed
CN-103517906-B 4H-imidazo [1,2-a ] imidazoles for electronic applications 巴斯夫欧洲公司 2016-08-24 CN disclosed