Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 3/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.35 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.35 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.34 |
| ▸ | PIKFYVE | Q9Y2I7 | 4/20 | 0.33 |
| ▸ | TTBK1 | Q5TCY1 | 3/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 3/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.31 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25061870 | 0.78 | ASIC3 (0.34) | PAK4PAK1PKN1ASIC3MAP3K14 | |
| SCHEMBL30092382 | 0.74 | MAP3K14 (0.45) | ALDH1A1PAK4PAK1PKN1ASIC3 | |
| SCHEMBL471131 | 0.74 | MAP3K14 (0.45) | ALDH1A1PAK4PAK1PKN1ASIC3 | |
| SCHEMBL3570374 | 0.73 | CHRNB2 (0.42) | ALDH1A1PAK4PAK1PKN1ASIC3 | |
| SCHEMBL3448180 | 0.72 | APP (0.54) | TSHRPAK4PAK1PKN1ASIC3 | |
| SCHEMBL2629434 | 0.72 | GRM5 (0.49) | ASIC3MAP3K14FFAR1HAO1 | |
| SCHEMBL14268091 | 0.70 | ASIC3 (0.49) | ALDH1A1TSHRASIC3FFAR1PTGES2 | |
| SCHEMBL19720165 | 0.70 | GABRA1 (0.36) | ALDH1A1TSHRPAK4PAK1PKN1 | |
| SCHEMBL1466752 | 0.69 | PAK4 (0.42) | ALDH1A1PAK4PAK1PKN1ASIC3 | |
| SCHEMBL13692781 | 0.68 | ASIC3 (0.34) | TSHRPAK4PAK1PKN1ASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | FUJIFILM CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-2202220-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
| EP-2202221-A1 | ACETYLENE COMPOUND | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | ALDH1A1 401/4885TSHR 3644/4885PAK4 4788/4885 |
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | KAT8, HDAC10, SSRP1 | ALDH1A1 1480/4885TSHR 4692/4885PAK4 4405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.