Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17676462 | 0.80 | LMNA (0.41) | PGK1PGK2HPGD | |
| SCHEMBL23798493 | 0.73 | TAS1R3 (0.42) | HPGD | |
| SCHEMBL20133884 | 0.70 | CYP1A2 (0.35) | — | |
| SCHEMBL20157077 | 0.70 | TP53 (0.37) | PGK1PGK2HPGDNOS3NOS1 | |
| SCHEMBL18432740 | 0.69 | NPSR1 (0.36) | PGK1PGK2NOS3NOS1NOS2 | |
| SCHEMBL28076217 | 0.69 | CYP3A4 (0.39) | HPGD | |
| SCHEMBL20231823 | 0.68 | PGK1 (0.50) | IDO1PGK1PGK2NOS3NOS1 | |
| SCHEMBL19120981 | 0.68 | NTRK1 (0.39) | HPGD | |
| SCHEMBL20865394 | 0.68 | MAOA (0.49) | HPGD | |
| SCHEMBL23222785 | 0.67 | NR3C1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |