Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylpiperazine SCHEMBL28280517 | 0.98 | PLD1 (0.41) | PLD1ADRB2NCF1TSHRNAPRT | |
| Methylpiperazine SCHEMBL28163289 | 0.90 | PLD1 (0.36) | PLD1ADRB2NCF1TSHRNAPRT | |
| Methylpiperazine SCHEMBL28170663 | 0.89 | GNAO1 (0.42) | PLD1ADRB2NCF1SLC6A4SIGMAR1 | |
| Methylpiperazine SCHEMBL28182481 | 0.85 | ADRB1 (0.44) | KDM4EALDH1A1HTR3EHTR3BADRB1 | |
| N-Methylpiperidine SCHEMBL18301353 | 0.84 | CHRNB2 (0.39) | PLD1ADRB2NCF1TSHRNAPRT | |
| Pyridine SCHEMBL19405324 | 0.83 | TSHR (0.53) | TSHRNAPRTTDP1KDM4EALDH1A1 | |
| Pyridine SCHEMBL11825162 | 0.80 | — | — | |
| N-Methyl Pyrrolidine (Nmp) SCHEMBL15264514 | 0.78 | TDP1 (0.47) | TSHRNAPRTTDP1KDM4EALDH1A1 | |
| Pyridine SCHEMBL1514812 | 0.78 | CYP3A4 (0.44) | PLD1ADRB2NCF1TSHRKDM4E | |
| Piperazine SCHEMBL28269434 | 0.78 | TSHR (0.53) | PLD1ADRB2NCF1TSHRNAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382913-B | A kind of method that solventless method prepares alkyl ketene dimer | 天津工业大学 | 2019-09-10 | — | — | CN | claimed |
| CN-109153654-A | The manufacturing method of isocyanuric acid derivative with 1 alkyl | 日产化学株式会社 | 2019-01-04 | — | — | CN | claimed |
| CN-109111397-A | A kind of quinoline aromatic ethylene analog derivative and its preparation method and application | 广东工业大学 | 2019-01-01 | — | — | CN | claimed |
| CN-109081361-A | A kind of multi-stage porous EU-1 molecular sieve and preparation method thereof | 中触媒新材料股份有限公司 | 2018-12-25 | — | — | CN | claimed |
| CN-108659243-A | A kind of branching type polyether-ether-ketone anion-exchange membrane and preparation method thereof | 大连理工大学 | 2018-10-16 | — | — | CN | claimed |
| CN-105121397-B | For detaching the method for 1,4-butanediol | 国际壳牌研究有限公司 | 2018-07-10 | — | — | CN | claimed |
| CN-105339065-B | Glycol is recycled using solvent extraction | 国际壳牌研究有限公司 | 2018-06-05 | — | — | CN | claimed |
| CN-107382913-A | A kind of method that solventless method prepares alkyl ketene dimer | 天津工业大学 | 2017-11-24 | — | — | CN | claimed |
| CN-106798745-A | A kind of medicine for treating tumor disease | 四川省人民医院 | 2017-06-06 | — | — | CN | claimed |
| CN-105985300-A | Continuous production method of piperidine | 山东泓达生物科技有限公司 | 2016-10-05 | — | — | CN | claimed |
| CN-110520422-A | Novel pyridone carboxylic acid derivatives or its salt | WAKUNAGA PHARMA CO LTD | 2019-11-29 | — | — | CN | disclosed |
| CN-106795259-B | Composition epoxy resin and its solidfied material | DIC株式会社 | 2019-11-12 | — | — | CN | disclosed |
| CN-106687532-B | The manufacturing method of the manufacturing method of azopigment, the manufacturing method of organic amine salt and organic amine salt and azo-compound and azo-compound | 富士胶片株式会社 | 2019-10-25 | — | — | CN | disclosed |
| CN-110372571-A | A kind of 2- (2,2- diaryl ethyl)-Cycloamine derivative or salt and synthesis and application and composition | 中国科学院大连化学物理研究所 | 2019-10-25 | — | — | CN | disclosed |
| CN-110357790-A | Compound and its purposes in synthesis Bu Waxitan bulk pharmaceutical chemicals | 福建海西新药创制有限公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-106029660-A | P2X 3 and/or P2X 2/3 compounds and methods | 阿萨纳生物科技有限责任公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-105985300-A | Continuous production method of piperidine | 山东泓达生物科技有限公司 | 2016-10-05 | — | — | CN | disclosed |
| CN-103965381-B | A kind of titanium tetrachloride initiator system altogether and the method being used for preparing high-activity polyisobutylene thereof | 北京化工大学 | 2016-08-24 | — | — | CN | disclosed |
| CN-103641772-B | The preparation method of (2R, 4R)-4-methyl piperidine-2-Ethyl formate compound | 北京成宇化工有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-103929960-B | Substituted (E) -N' - (1-phenylethylidene) benzoyl hydrazine analogs as histone demethylase inhibitors | 犹他大学研究基金会 | 2016-08-17 | — | — | CN | disclosed |