Methylpiperazine

Methylpiperazine

SCHEMBL28170663

CCCCCC.CN1CCNCC1.c1ccncc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GNAO1 P09471 7/20 0.42
GNAI3 P08754 6/20 0.42
GNAI1 P63096 6/20 0.42
ADRB2 P07550 1/20 0.35
NCF1 P14598 1/20 0.35
PLD1 Q13393 1/20 0.35
SLC6A4 P31645 1/20 0.35
SOD3 P08294 2/20 0.35
HRH4 Q9H3N8 1/20 0.35
SIGMAR1 Q99720 1/20 0.34
TBXAS1 P24557 1/20 0.33
FLT3 P36888 1/20 0.33
TYRO3 Q06418 1/20 0.33
MERTK Q12866 1/20 0.33
GAS6 Q14393 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylpiperazine SCHEMBL28076386 0.89 PLD1 (0.42) ADRB2NCF1PLD1SLC6A4SIGMAR1
Methylpiperazine SCHEMBL28163289 0.87 PLD1 (0.36) ADRB2NCF1PLD1SLC6A4CYP3A4
Methylpiperazine SCHEMBL28280517 0.87 PLD1 (0.41) ADRB2NCF1PLD1SLC6A4SIGMAR1
Pyridine SCHEMBL28267914 0.86 SOD3 (0.48) GNAO1GNAI3GNAI1SOD3SIGMAR1
Benzene SCHEMBL28877638 0.84 SIGMAR1 (0.47) GNAO1GNAI3GNAI1SOD3SIGMAR1
Pyridine SCHEMBL28152800 0.84 SIGMAR1 (0.47) GNAO1GNAI3GNAI1SOD3SIGMAR1
Pyridine SCHEMBL28143472 0.83 SOD3 (0.49) GNAO1GNAI3GNAI1SOD3SIGMAR1
Methylpiperazine SCHEMBL28259666 0.82 GNAO1 (0.50) GNAO1GNAI3GNAI1SIGMAR1
Octane SCHEMBL28373017 0.80 GNAO1 (0.53) GNAO1GNAI3GNAI1SOD3SIGMAR1
Heptane SCHEMBL28268875 0.80 GNAO1 (0.53) GNAO1GNAI3GNAI1SOD3SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107140657-B A kind of preparation method of IZM-2 molecular sieve 中国科学院上海高等研究院 2019-04-23 CN disclosed
CN-107140657-A A kind of preparation method of the molecular sieves of IZM 2 中国科学院上海高等研究院 2017-09-08 CN disclosed