Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997715 | 0.97 | HTR4 (0.47) | HTR4HTR1ASLC6A4HTR2AGRM2 | |
| SCHEMBL28076881 | 0.92 | HTR1A (0.45) | HTR4HTR1ASLC6A4HTR2AGRM2 | |
| SCHEMBL28076883 | 0.89 | HTR4 (0.46) | HTR4HTR1ASLC6A4HTR2AGRM2 | |
| SCHEMBL28076703 | 0.88 | SLC6A2 (0.47) | HTR4HTR1ASLC6A4MEN1KMT2A | |
| SCHEMBL28956404 | 0.84 | SLC6A2 (0.47) | HTR4SLC6A4MEN1KMT2AMAPK14 | |
| SCHEMBL27997533 | 0.84 | SLC6A2 (0.47) | HTR4SLC6A4MEN1KMT2AMAPK14 | |
| SCHEMBL28830821 | 0.82 | ADRA1D (0.49) | HTR4CCR3MEN1KMT2A | |
| SCHEMBL28076798 | 0.82 | HTR1A (0.55) | HTR1ASLC6A4HTR2ACCR3OPRM1 | |
| SCHEMBL28076576 | 0.81 | GRIN2B (0.41) | HTR4HTR1ASLC6A4MEN1KMT2A | |
| SCHEMBL28076710 | 0.81 | TSHR (0.52) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980184-B | Piperidine compounds, medical composition and its use containing this compound | 爱思开生物制药株式会社 | 2016-08-24 | — | — | CN | claimed |